Custom Peptides
Cayman Chemical aEthylamInopentIophenonhy 10mg
A substituted cathinone that is an analog to ethcathinone, differing by having propyl rather than methyl at the α position; intended for forensic and research purposes.
Cayman Chemical 2-CMethylgunosIn 10mg
An active metabolite of BMS-986094; inhibits replication in genotype 1b HCV replicon cells (EC50s = 5.2 and 3.2 µM in ELISA and luciferase assays, respectively); inhibits replication of the Zika virus clinical isolate ZIKVPE243 in HBMECs, SH-HY5Y cells, and Vero cells (EC50s = 0.88, 2.09, and 1.25 µM, respectively) but is toxic to newborn mice infected with ZIKVPE243 at postnatal day 2 at 25 mg/kg per day
Cayman Chemical 5-fluoro THJ 10mg
A derivative of THJ 018 featuring a fluorine atom added to the terminal carbon of the pentyl group and an 8-aminoquinoline replacing the naphthalene group; intended for research and forensic applications
Cayman Chemical 7 8-DIhydronpterIn 10mg
A pteridine with antioxidant activities; scavenges DPPH radicals in a cell-free assay at 20-100 µM; inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases TBARS produced by THP-1 cells cultured with LDL at 2-10 µM; inhibits necrosis induced by oxLDL in U937, but not THP-1, cells at 200 µM
Cayman Chemical Isotachysterol 3 10mg
An impurity in the preparation of vitamin D3; stimulates intestinal calcium transport and bone calcium mobilization in control, as well as in anephric, rats fed a low-calcium and vitamin D-deficient diet at 5 UG/animal
Cayman Chemical 4-O-MethylhonkIol 10mg
A phenol with diverse biological activities; active against the bacteria B. subtilis, S. aureus, and M. smegmatis (MIC = 2.5 UG/ml for all) and the fungus T. mentagrophytes (MIC = 1.25 UG/ml); inhibits LPS-induced activation of NF-kB and production of NO in RAW 264.7 macrophages at 10 and 30 µM; reduces carrageenan-induced paw edema in mice at 20 and 200 mg/kg; reduces neuronal apoptosis and escape latency in the Morris water maze in a mouse model of Aβ42-induced Alzheimer's disease at 1 mg/kg; reduces plasma cholesterol and triglyceride levels, ameliorates hepatic steatosis, and improves insulin resistance in a mouse model of high-fat diet-induced obesity
Cayman Chemical AmsacrInhydrochlorIde 10mg
A topoisomerase II poison; stimulates formation of a complex between DNA and topoisomerase II in which the DNA is cleaved and topoisomerase II remains covalently linked to the 5’ end of the DNA cleavage products; inhibits the DNA strand-passing activity of topoisomerase II at a concentration of 20 μg/ml; reduces growth of LoVo human colorrectal carcinoma and T1 human lymphoma cells in a dose-dependent manner; antitumor activity against several murine leukemia, melanoma, lung, colon, and mammary xenograft mouse models
Cayman Chemical C12 CeramIded18 112 0 10mg
A naturally occurring ceramide; is formed when C12 sphingomyelin is hydrolyzed by ASM; substrate for acid ceramidase, an enzyme which has 2- to 12-fold higher activity in fibroblasts from patients with Farber disease; found in the Wharton's jelly of babies born to women with pre-eclampsia
Cayman Chemical 2DeoxyadenosIn5OdIphos 10mg
A nucleotide diphosphate; inhibits the polymerization of ADP and CDP by E. coli or P. fluorescens polynucleotide phosphorylase at 0.23 mM; levels are increased in erythrocytes isolated from patients with adenosine deaminase deficiency and SCID
Cayman Chemical Phenprocoumon 10mg
An anticoagulant and vitamin K antagonist; inhibits the activity of wild-type VKOR (IC50 = 4.2 nM), as well as a variety of mutant VKORs (IC50s = 5.1-835 nM), in cell-based reporter assays; inhibits prothrombin complex synthesis in rats in a dose-dependent manner
Cayman Chemical Uncaa yncopyla sutn 10mg
An indole alkaloid; reduces glutamate-induced cytotoxicity in primary rat cerebellar granule neurons from 100-300 µM; inhibits nicotine-induced dopamine release in PC12 cells from 1-100 µM
Cayman Chemical ChlorothIazIde 10mg
An analytical reference standard categorized as a thiazide diuretic; intended for analytical forensic applications
Cayman Chemical KaempfRol 3nohSpRIdosID 10mg
A flavonoid with antioxidant and antidiabetic activities; scavenges DPPH radicals (IC50 = 79.6 UG/ml); increases glucose uptake in isolated rat soleus muscle at 1 and 100 nM; increases glycogen synthesis in isolated rat soleus muscle at 1 µM; reduces serum glucose levels in a rat model of alloxan-induced diabetes at 100 mg/kg